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05/05/2010 11:24 PM


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Fibromyalgia misconceptions: Interview with a Mayo Clinic expert

Get the facts about these common fibromyalgia myths. Learning all you can about fibromyalgia is the first step toward gaining control of your symptoms.

By Mayo Clinic staff

Connie Ludtke, R.N.

Fibromyalgia is a widely misunderstood condition that causes widespread pain and fatigue.

If you've been diagnosed with fibromyalgia and are trying to learn all you can about the condition, you may come across some myths and misconceptions about fibromyalgia.

In this interview, Connie Luedtke, R.N., the nursing supervisor of the Fibromyalgia and Chronic Fatigue Clinic at Mayo Clinic, Rochester, Minn., answers questions about some of the most common misconceptions about fibromyalgia.

What is the most common misconception about fibromyalgia?

The top misconception is that people think fibromyalgia isn't a real medical problem or that it is "all in your head."

It's sometimes thought of as a "garbage-can diagnosis" — if doctors can't find anything else wrong with you, they say you have fibromyalgia.

Being diagnosed with fibromyalgia does require that you meet specific criteria, including painful tender points above and below the waist on both sides of the body.

There's a lot that's unknown about fibromyalgia, but researchers have learned more about it in just the past few years.

In people who have fibromyalgia, the brain and spinal cord process pain signals differently; they react more strongly to touch and pressure, with a heightened sensitivity to pain.

It is a real physiological and neurochemical problem.

Why does this misconception persist?

In our society, people tend to think that there is a cure or a fix for every medical problem. You go to the doctor, expecting he or she will fix whatever's wrong with you with medication or surgery.

It's frustrating to people with fibromyalgia because the traditional treatment approach isn't effective.

And it's also frustrating to health care providers because they want to help people.

But there's no easy fix. It takes lifestyle changes and small steps toward achieving wellness. It's a process.

How have misconceptions about fibromyalgia changed over the years?

More people understand that fibromyalgia is a real problem, often because they know someone who has it — perhaps a sister or daughter or mother.

Health care providers are seeing that people who have fibromyalgia can manage their symptoms with lifestyle changes to improve their overall functioning and quality of life. And there's hope for the future.

Are people who have fibromyalgia more likely to try unproven remedies?

People who have any chronic disease that doesn't respond to conventional treatment often turn to other types of remedies.

People who have fibromyalgia tend to use more dietary supplements. Some people think that there's a magic diet for fibromyalgia.

They think that they should avoid refined flour and sugar, sugar substitutes, the caramel color in some soft drinks, or carbonated drinks in general.

But there hasn't been any research-based evidence demonstrating that any of these substances cause the symptoms, nor that removing these substances from your diet works to make the pain go away.

There may be anecdotal evidence — people who say that something helps relieve their symptoms — but there's no clearly identified problem foods or magical diet cure yet.

Is a placebo effect at work here?

The power of the mind is a real factor in pain perception. For example, studies have shown that anxiety that occurs in anticipation of pain is much more problematic than the pain experience itself. In that sense, the mind has a negative impact on symptoms.

Many of the people who come to our fibromyalgia clinic are perfectionists who have very high expectations for themselves; likewise they can't adjust to more realistic expectations after they develop fibromyalgia symptoms.

These people have difficulty learning to relax.

They may push through the pain and keep doing activities to the point they crash and burn and need extra time to recover.

So the pain keeps reinforcing itself in a never-ending cycle. People report lower levels of pain when they can slow their heart rate by deep breathing and doing other relaxation techniques.

In our clinic, we teach people about tools they can use to tap into what they have within their own power.

Can misconceptions about fibromyalgia be harmful?

If people with fibromyalgia believe there is no help for them, they're going to stay stuck. Even if there isn't a cure, there are treatments that can really improve their quality of life.

When people learn they have fibromyalgia, they can go through the stages of grief and loss — including experiencing anger and attempts at bargaining.

When they get to the peace of acceptance, that's when they can realize there are limits to what medical technology can do.

There's no magic surgery or pill that can fix this.

They need to recognize that it's OK to ask for help with things and that it's OK to give themselves time for exercise and relaxation each day.

They need to make their own health a priority.


0.Questions and answers about fibromyalgia. National Institute of Arthritis and Musculoskeletal and Skin Diseases. default.asp.

Accessed Jan. 20, 2010.

0.Fibromyalgia. American College of Rheumatology. diseases_and_conditions/fibromyalgia.asp?aud=pat.

Accessed Jan. 20, 2010.

0.Luedtke CA (expert opinion).

Mayo Clinic, Rochester, Minn. Jan. 19, 2010.0.Klippel JH, et al.

Good Living With Fibromyalgia. Atlanta, Ga.: The Arthritis Foundation; 2006.

0.Wahner-Roedler DL, et al.

Use of complementary and alternative medical therapies by patients referred to a fibromyalgia treatment program at a tertiary care center.

Mayo Clinic Proceedings. 2005;1:55.

0.Fibromyalgia and CAM: At a glance. National Center for Complimentary and Alternative Medicine. Accessed Jan. 20, 2010.

0.Holton KF, et al.

Potential dietary links to central sensitization in fibromyalgia: Past reports and future directions. Rheumatic Disease Clinics of North America. 2009;35:409.

0.Sullivan MJ, et al.

Theoretical perspectives on the relation between catastrophizing and pain. Clinical Journal of Pain. 2001;17:52.AR00056

March 19, 2010

© 1998-2010 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Fibromyalgia misconceptions: Interview with a Mayo Clinic expert


05/05/2010 11:45 PM
Posts: 33492
VIP Member
I'm an Advocate

Fibromyalgia: Is Fibromyalgia Real?

Neurology Now

September/October 2009; Volume 5(5); p 29-32




•longstanding skepticism

•new clues from brain research

•same stimulus, more pain

•options for treatment


A growing body of information suggests fibromyalgia is a true neurologic disorder.

Like many of his colleagues, John Kissel, M.D., used to think that fibromyalgia wasn't a real condition.

Dr. Kissel, a neurologist and the co-director of the MDA/ALS Center at Ohio State University, thought it was a wastebasket diagnosis-a dumping ground for malingering, drug-seeking patients with unexplained pain, fatigue, and depression.


[ Click here to enlarge ]

Then he saw patients that began to change his mind.

He still remembers one woman in her 40s, a professional trial attorney from Columbus, OH. She had developed debilitating fatigue and horrible muscle pain and tenderness about a month after getting over a mild case of the flu.

After performing a number of tests, I went in to speak with her and mentioned fibromyalgia, Dr. Kissel recalls. She asked, 'What's that?' I said,

'You haven't heard of fibromyalgia? People are talking about it all over the place.' She said to me, 'I work 14 hours a day as a trial attorney-I don't do outside reading.'

She wasn't depressed. She was still working. But she had all the typical symptoms of fibromyalgia. That was a formative experience in my thinking about the condition.

Today, more and more neurologists are coming around to the idea that fibromyalgia is a real disorder, and one that should be managed, or at least co-managed, by neurologists who care for chronic pain-not only the rheumatologists who originally identified the condition some 100 years ago.

Neurologists have become more educated about the diagnosis and treatment of fibromyalgia. - LYNNE MATALLANA, FOUNDER OF THE NATIONAL FIBROMYALGIA ASSOCIATION

Fibromyalgia has long presented a puzzle for doctors. It's considered a syndrome-a collection of related symptoms and problems without an identifiable cause-rather than a disease.

Those related symptoms include:

* Chronic widespread pain, often accompanied by numbness, tingling, and burning

* Multiple tender points throughout the body

* Severe fatigue

* Sleep problems

Pain networks in the brains of fibromyalgia patients seem to be more easily activated than in people without the disorder.

To be diagnosed with fibromyalgia, a person must have had widespread pain in all four quadrants of the body for at least three months, and tenderness or pain when pressure is applied in at least 11 of 18 identified tender points.

Fibromyalgia was originally thought to be a rheumatologic condition because-like diseases such as rheumatoid arthritis-it is characterized by musculoskeletal pain. But research has since shown that there are no abnormalities in the musculoskeletal system in people with fibromyalgia.

Instead, the problem appears to lie in the pain processing pathways of our central nervous system-the bailiwick of neurologists.

Today, both rheumatologists and neurologists treat fibromyalgia.

The National Fibromyalgia Association estimates that between three percent and six percent of the population has fibromyalgia-mostly women, but some men and children as well.

However, with a flimsier body of research than many other chronic conditions and no blood test to diagnose the disorder, controversy has swirled around fibromyalgia for years.

It's also easily confused with other conditions, such as rheumatoid arthritis and lupus (in fact, some patients have both).

Lynne Matallana, the founder and president of the National Fibromyalgia Association, originally saw a rheumatologist for her fibromyalgia.

Recently she has also been seeing a neurologist to help with the overlapping conditions, such as migraines and restless leg syndrome, that also cause her distress.

Just like everyone with fibromyalgia, I have to deal with comorbid conditions that are often treated by neurologists, Matallana says.

When I started experiencing insomnia and daytime sleepiness, for example, I was referred to a neurologist who specialized in sleep disorders.

Unlike several years ago, neurologists have become more interested and educated about the diagnosis and treatment of fibromyalgia. As a patient this is extremely exciting because they bring a new perspective.


In the past, there has been legitimate reason for skepticism about fibromyalgia, Dr. Kissel acknowledges.

The majority of research in fibromyalgia was not adequate, he says.

Studies would pick some parameter and look at it only in patients with fibromyalgia and sometimes in normal controls, without comparing them to people with other chronic pain conditions, patients with depression, or to patients with other muscle diseases.

What's more, some physicians tended to view it as a grab-bag condition, diagnosed only when the doctor couldn't find anything else.

Patients would come in and say, 'I have muscle pain.'

The doctor would do all kinds of tests-electromyography [a test for abnormal electrical activity in the muscles], blood work, muscle biopsies, and imaging, and if all that was negative, then voilà, it was fibromyalgia, he says.

But that's not the way you diagnose, Dr. Kissel stresses.

It's as if someone came in with a classic migraine headache and you gave the patient scans, brainwave tests, and arteriograms [imaging of the blood vessels], and if you still didn't know what it was, you said they had migraine.

You diagnose migraine by what patients tell you and the way they look in the exam room, and that's the way you diagnose fibromyalgia, too.

The fact that abnormalities don't show up on standard neurological tests like electromyelograms and nerve-conduction studies (tests that measure how fast electrical impulses travel between nerves) is not evidence that fibromyalgia doesn't exist, says John Farrar, M.D., Ph.D., a neurologist and pain specialist at the University of Pennsylvania School of Medicine.

There may be a few people in the world who complain of [fibromyalgia] in order to get drugs and attention, but the number of real malingerers is relatively small.

The patients I see have very real pain, and it's up to us as doctors to figure out what the underlying major contributors to that pain are.

It hasn't just been doctors who are skeptical of fibromyalgia-many patients have been, too.

Just recently I saw two patients who had both been to the Cleveland Clinic previously. One was the wife of a physician.

They had both been told that they had fibromyalgia but neither wanted to accept it, despite the fact that they had all the criteria, says Dr. Kissel.

Probably three-quarters of the patients I now see with fibromyalgia have been diagnosed by another doctor, but neither the doctor nor the patient is satisfied with the diagnosis.

They want another diagnosis that they think will be more treatable.


New and better research pointing to possible underlying causes of fibromyalgia seems to be winning over at least some of the skeptics.

Using tools like functional MRI, which show the brain's response to pressure and heat stimuli, researchers have been able to measure how people with fibromyalgia process stimuli like pain and pressure.

Some key differences have been discovered between fibromyalgia patients and those without the condition.

Researchers at the University of Michigan in Ann Arbor have found that patients with fibromyalgia have what's called a hyperexcitable nervous system.

In other words, pain networks in their brains are more easily activated than people who don't have fibromyalgia.

Other researchers have also found impairments in a specific brain region that helps to inhibit the body's response to pain among people with fibromyalgia.

So on the one hand, people with fibromyalgia process any somatic sensory information-for example, light to moderate pressure-as painful, which comes as the result of hyperexcitability in the central nervous system, says pain specialist Miroslav Backonja, M.D., a professor of neurology, anesthesiology, and rehabilitation medicine at the University of Wisconsin School of Medicine and Public Health.

Making the problem even worse, the body's pain modulation fails to engage.

The body's pain modulation system can help to dial down just how intensely we perceive a painful stimulus.

In this way, fibromyalgia is somewhat similar to epilepsy.

There's hyperexcitability in the nervous system on the one hand, and a failure of inhibition on the other, Dr. Backonja says.

Which helps explain why pregabalin-a medication that is used to control epilepsy-can also be used to relieve fibromyalgia pain.

Yunxia Wang, M.D., used to be a fibromyalgia-skeptical neurologist as well-until treating a patient with pregabalin helped to change her mind.

Four or five years ago, a patient came to see me with a diagnosis of fibromyalgia, says Dr. Wang, a neurologist at the University of Kansas who says that about 15 percent of her practice now involves patients with fibromyalgia.

She also had multiple sclerosis. While treating her for MS, I realized that she was using her steroid medication too much. ******************************

She told me it was because of pain.

I wondered if it was because of the fibromyalgia, so I added her on pregabalin without changing her MS treatment.

For over a year and a half, she hasn't had an attack and she's doing much better with her pain.

So a patient could have an underlying neurologic disease and also have fibromyalgia.

I think there's really been a shift, and the brain imaging is what's doing it, says Matallana.

We're seeing changes in the brain in fibromyalgia, and finally the neurologists are saying, 'You're talking my talk. This is interesting and I don't want to be left out.'

Not all neurologists are embracing fibromyalgia, however. It's a difficult condition to take care of. The patients have chronic pain, they call a lot, and they tend to have a lot of comorbidities, says Dr. Kissel.

Comorbidities are other conditions that exist alongside the main disorder-with fibromyalgia they often

include depression, anxiety, headache, irritable bowel syndrome, chronic fatigue syndrome, lupus, and rheumatoid arthritis.

They're very much like chronic headache patients in this regard.

Matallana agrees that the interest in fibromyalgia among neurologists at this point is largely among researchers, pain specialists, and those at academic centers.

I don't think it's trickled down to the average neurologist in practice yet, she says. But that may change soon.

Same Stimulus, More Pain

These pictures show functional magnetic resonance imaging (fMRI) responses to pressure applied to the left thumb in patients with fibromyalgia versus those without.

The chart shows that for fibromyalgia patients, low pressure produced a high pain level (red triangle); for those without fibromyalgia (blue square), similar pressure produced a low level of rated pain.

The brain images show common regions of activation in fibromyalgia patients (red) who received low pressure versus non-patients (green) who received high pressure.

The similar pain intensities produced by significantly less pressure in the patients resulted in overlapping areas (shown in yellow).



[ Click here to enlarge ]


But Dr. Backonja argues that neurologists, especially those who specialize in pain, have a responsibility to take fibromyalgia on. It would be scary and sad for our profession if mounting scientific information were ignored, he says.

There's a growing body of information clearly pointing to this as a neurological disorder, and while we can't cure it, there is a pretty reasonable way to apply treatment strategies.

There are now three medications approved by the Food and Drug Administration (FDA) for the treatment of fibromyalgia.

In addition to pregabalin, which was the first to gain approval, duloxetine and milnacipran can also be prescribed for fibromyalgia.

Duloxetine is also approved for the treatment of depression, anxiety, and painful diabetic neuropathy;

and milnacipran for the treatment of depression.

Doctors may also prescribe low doses of antidepressants to boost serotonin levels, helping to improve sleep and relieve pain.


[ Click here to enlarge ]

In addition to medication, the patient needs to be engaged in figuring out how to help him- or herself, says Dr. Farrar.

This can include physical therapy, rehabilitative exercise, yoga, self-hypnosis, biofeedback-things that allow the brain to be retrained to help deal with the pain.

None of these are right for everybody, of course. For example, some people prefer exercise therapy to yoga.

How successful are these treatments?

For people initially diagnosed with fibromyalgia, Dr. Farrar says that the chances of neurologists being able to help make them at least somewhat better or manage their pain are high-about 75-to 90-percent.

By the time someone comes to see a specialist, they have probably had some of the simpler therapies, so the likelihood may have gone down a bit. But we're always able to help people in some way.

We work with the patient to focus on what works and what doesn't, helping them to manage their discomfort and disability.

More options are on the horizon, as scientists learn more about pain and the nervous system in general and fibromyalgia in particular.

We're learning a lot more about nerve-related pain, and although there aren't any obvious pathways that are focused on fibromyalgia, there are still some new agents that I think will allow us to begin to treat patients for underlying abnormalities, says Dr. Farrar.

He predicts that the prospects for at least two or three additional therapies for fibromyalgia over the next 10 years are very good.

That said, people shouldn't set their expectations too high, he says.

I doubt we'll be able to get to the point where there is zero pain, but we can make it like arthritis-the pain is there, but people are functional and can do the things they need to do.

©2010 American Academy of Neurology - All Rights Reserved


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