Why wear a ribbon?

"I wear this ribbon because someone i know has Lyme disease." (lullabyrose)

MDJunction to me

"MD Junction is my second home, Where my friends are always ready with advise , compassion and a kind word or two. Where I can always be myself never having to put on a brave face or smile if I don't feel like it.
Thank you MD Junction
" (mpmom)
We comply with the HONcode standard for trustworthy health information:
verify here.
Lyme Disease Support Group
A community of patients, family members and friends dedicated to dealing with lyme disease, together.
Join This Group
Group Home   Forums   Articles   Members (752)   Diaries   Leaders   Guidelines
Related discussions:
12/02/2008 05:56
cave76

Many case reports support the adaptation of a longer-term treatment approach. Liegner has published case studies detailing Bb's ability to evade antibiotic destruction, including "Recurrent erythema migrans despite extended antibiotic treatment with minocycline in a patient with persisting Borrelia burgdorferi infection" (Journal of the American Academy of Dermatology, 1993; 28: 312-314).

Numerous full text articles detailing persistence or relapse of LD despite "appropriate" or "conventional" antibiotic therapy have also been published in peer-reviewed journals.

Among the most compelling published evidence of chronic infection despite prolonged antibiotic therapy is the case study "Seronegative Chronic Relapsing Neuroborreliosis," (Eur Neurol 1995; 355: 113-17).

It details a patient whose serum was consistently negative for free antibodies for Bb infection, but had laboratory evidence of active infection in the cerebrospinal fluid (CSF). The patient, a previously healthy 58-year-old woman, received four courses of intense antibiotic therapy: 3-weeks of intravenous ceftriaxone followed by 8-weeks of ceftriaxone; 2 weeks of intravenous ceftriaxone followed by 19 weeks of doxycycline; 3-weeks intravenous treatment followed by additional treatment with doxycycline; and 2 weeks of intravenous ceftriaxone.

Evidence of active infection was found each time after intense prolonged antibiotic therapy was administered.

Relapse occurred soon after treatment was stopped and Jarish-Herxheimer episodes were experienced each time treatment was initiated. (J-H reactions are symptoms that include fever and nausea and are believed to be cause by the body's initial reaction to toxins from dead Bb.) When the patient was given clarithromycin for 22 months, no new symptoms or deficits occurred.

http://www.lyme.org/lymelight/trtcontrov.html

Reply  


12/06/2008 12:09
momcat1011
Posts: 15
New Member

Send a PM
Give a Hug
I have had Lyme since May 1st of this year and in my case the antibiotic treatment ( in my opinion) is necessary to reduce secondary infections. Secondary infections occur due to immune suppression. In my case, I became immune suppressed about 10 weeks post infection, even though I had the proper antibiotic treatment. Thus, in my opinion, a study should be conducted to evaluate the use of moderate antibiotic use after infection to see if secondary infections can be better controlled. I believe most of the studies do not ask the right question.

More importantly, how can the organism that causes LYME be killed? The organism that causes LYME infection, in my experience, seems to be more susceptible to agents such as azole derivatives more commonly used to treat higher organisms. It seems to me that the bacteria must some how exist symbiotically with a higher organism(s, or perhaps it up regulates certain protective genes if it challenged by a preexisting organism in the host. It is unfortunate that more research is not conducted in this field as physicians seem to be completely in the dark as to how to treat this infection properly or prevent secondary infections. I frankly had more faith in the medical system --- but based on this infection I can see how flawed medical care really is.


Popular posts by momcat1011
    testing
    tick bite in hotel
    ELISA
Reply  


12/06/2008 15:30
buckron
Posts: 537
Member

Send a PM
Give a Hug
Wow..Thats a toughy azole derivatives, an antifungal agent ? Is that correct? If that is the case then i may be on the right track and this just might help you. I use P73 Oil of Oregano a very strong antifungal agent.I read its stronger and more effective than Diflucan,I know it Killing something Samento could not get at in my poor excuse of a body...plus it will get places abx can not.I try to simplify Lyme..but i do believe in its antifungal properties plus its non toxic always a bonus in this battle!
Reply  


12/06/2008 15:39
buckron
Posts: 537
Member

Send a PM
Give a Hug
momcat..Let me add something..i am not sure i understand your original post.Are you talking about spirochetes in the protective biofilm mode? Where abx have a hard time reaching and destroying them? Thats why i chose essential oils..to hopefully eradicate them as they infiltrate every cell in your body..it may be a stab in the dark against protected spirochetes but i am banking on them to do the job..did i enter the subject area you were seeking? Hope so Ron
Reply  


12/06/2008 21:25
shortangle2

Give a Hug
So Cave my darling,

The bottom line was your bottom line. When given abx continutally, the lyme was at least stopped. Cured, I don't know.

Are you planning to publish Fallon's neuro study. It would be interesting along with these.

Reply  


12/07/2008 07:23
cave76

Give a Hug
Momcat,

There are so many comments I want to make (as a non-doctor but somewhat knowledgeable position as having read Lyme forums for over a decade)AND knowing a bit about the science of Lyme et al.

I'll start with just one:

*****In my case, I became immune suppressed about 10 weeks post infection*****

How is it you 'know' you are immune suppressed. It surely wasn't by the limited CD57 test was it? That test just looks at a tiny portion of the 'immune system'. Plus it's widely known (but not accepted by people who haven't followed that test, even docs) that it's not a definitive test.

So---- if you've had a complete immune system work-up that's an entirely different matter.

Reply  


12/08/2008 12:00
momcat1011
Posts: 15
New Member

Send a PM
Give a Hug
In concluded that my immune system is suppressed based on clinical symptoms that began about 10-12 weeks after the tick bite. I initially had 3 weeks of antibiotics. If is is an autoimmune reaction, then once the infection is eliminated then presumably the immune suppression will end.

An ergosterol synthesis inhibitor such as an azole derivative theoretically should not prevent growth of Borrelia burgdorferi unless the bacteria exists symbiotically with a higher organism. However, it appears to be working in my situation. However, that being said I would not want to go without some form of antibiotics even for a short period of time.


Popular posts by momcat1011
    testing
    tick bite in hotel
    ELISA
Reply  



Start a New Discussion

Disclaimer: The information provided in MDJunction is not a replacement for medical diagnosis, treatment, or professional medical advice. Read more.
Contact Us | Bookmark Us | Add a Doctor | For Doctors | FAQ | Awareness Ribbons
About Us | Terms & Conditions | Privacy | Spread the Word | Advertise
Copyright (c) 2008 MDJunction.com All Rights Reserved