Lyme Disease Support Group

My 5 year old had positive bands- 31, 34, 41, 58, 66 and IND on 83-93 (for IgM). On his IgG he was only positve on 41.

My 2 year old's IgM was positive 18, 28, 30, 34, 41, 58, and IND on 31 and 83-93. The IgG was positive on 41.

My 6 year old's IgM is positive on 41, 66 and IND on 31, 34 and 39. The IgG is positve on 41.

My pediatrician has no idea how to read the results and my Lyme Dr. won't be in until next week.

None of the kids have any specfic symptoms, but have things that may involve the disease. My 6 year old has Cerebral Palsy and my 5 year old gets headaches and can be moody. I had them tested since I don't know when I was infected.

I am not sure how we are going to procede with the treatment.

I am still new to this disease myself, so if anyone had any thoughts, suggestions or ideas where I can get more accurate info. please let me know!

Thank you!

Only one of these Borrelia burgdorferi genus specie specific bands is needed to confirm that there is serological evidence of exposure to the Borrelia burgdorferi spirochete and can confirm a clinical diagnosis of Lyme disease.

(More info pages 12 & 13 "Western Blot Made Easy":

http://www.publichealthalert.org/PHA%20JUNE%2007.pdf )

Igenex Western Blot Break Down by band

9 cross-reactive for Borrellia

12 specific for Bb

18 highly specific to Lyme (Many LLMD's say if this band alone is positive, you have lyme - see link above)

20 cross-reactive for Borrellia

21 unknown

22 specific for Bb, probably really the 23/25 band

23-25 outer surface protein C (OspC), specific for Bb

28 unknown

30 unknown; probably an outer surface protein; common in European and

one California strain - Has cross-reactivity with several different types of viruses

31 outer surface protein A (OspA), specific for Bb - Has cross-reactivity with several different types of viruses

34 outer surface protein B (Osp; specific for Bb

35 specific for Bb

37 specific for Bb

38 cross-reactive for Bb

39 is a major protein of Bb flagellin; specific for Bb

41 flagellin protein of all spirochetes; this is usually the first to appear after a spirochete infection but is NOT specific to Lyme (i.e, other spirochete diseases have flagellas - see link above "Western Blot Made Easy" for more info)

45 cross-reactive for all Borellia

50 cross-reactive for all Borrellia

55 cross-reactive for all Borrellia

57 cross-reactive for all Borrellia

58 unknown but may be a heat-shock Bb protein

60 cross reactive for all Borrellia

66 cross-reactive for all Borrelia, common in all bacteria

83 specific antigen for the Lyme bacterium, probably a cytoplasmic membrane

93 unknown, probably the same protein in band 83, just migrates differently in some patients[/b]

An IgM positive test result means more recent & likely currently active infection. IgG positive means previous exposure to the bacteria or older infection of Lyme. If no symptoms are present with IgG positive, it may mean an "inactive" LD infection. No matter the results, please remember LD is a clinical diagnosis, you can have a negative test and still have Lyme Disease and the co-infections, even through the best labs. If you have symptoms, you need treatment.

also, some good info:

http://www.mdjunction.com/forums/lyme-disease-support- forums/medicine-treatments/Itemid=217/func=post/do=reply/ replyto=1652292

mom, please print off dr. c's western blot igm & igg blood test info right above this; you'll use this over & over. the more you read the info, the more you learn and it eventually sinks into our neuro lyme minds.

also print off the link in my WELCOME LETTER TO YOU: KIDS/ADULTS DOSAGES/MEDS...it's spaced out for easier reading ok.

please post in LLMD REQUEST FORUM; 1st forum at the top of the home page of lyme ok

show you have 3 kids & their AGES in subject line plus what state you live in

best wishes to your entire family hugs/kisses

bettyg, iowa lyme activist/group leader

Post edited by: Bettyg, at: 07/02/2010 11:53 PM