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CD57 - immune system suppression



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05/06/2008 11:08
saranichols
Posts: 6
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Okay....I'm wondering if others are having this test done. My doctor had this done and it came back pretty bad. He said it relates to our immune system. According to some research that I've done, this can be suppressed by Lyme or HIV. I of course was tested for HIV and it was negative...I guess that just has to be ruled out in cases like this. That is all I have been able to come up with. Also, does anybody else know how low is "risky" low? I was just told that ideally, my CD57 would be anywhere from 150-250. Well, mine is 18. (eighteen) And if it is low, what exactly does that mean? What are other doctors saying? Is there any way to increase this? I'm just looking and searching for as much information as I can. Thanks so much! If you dont' want to post a reply, please Private Message me....I'm needing information badly on this.
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05/06/2008 13:13
Mizuiro
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http://www.canlyme.com/lymeconf04.html

This is a site I found interesting and if you scroll down it has a short article on CD57. It explains what it is. I decided to copy and paste that particular article but included the site in case anyone wants to read it.

"Dr. R. Stricker: Using the CD57 Natural Killer Cell Marker to Measure Treatment Progress

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd==Retrieve&db==PubMed&list_uids=.088407&dopt=«stract

One of the difficult things about treating chronic Lyme patients is figuring out when to stop antibiotics, since the antibody and PCR tests are so unreliable. Dr. Stricker has been doing research that measures the CD57 Natural Killer (NK) Cell levels as a way of determining if a chronic lyme patient is getting better. (The CD57 Natural Killer Cell is an aggressive white blood cell or "lymphocyte" that seeks out invading germs and destroys them.) It appears that Bb and all the coinfections somehow disable the production of the CD57 natural killer cells. (The "Stricker Panel," which is ordered by many Lyme Literate Physicians measures this immune system marker, among others.)

www.anapsid.org/lyme/strickerpanel.html

In his study of 89 chronic Lyme patients over a year, he found that patients with chronic Lyme disease and very low CD57 NK levels have significantly more coinfections, delayed diagnosis, more neurologic disease and persistent immunologic defects, compared to patients with higher CD57 NK levels.

He talked about how the Bb organism has more than 1,500 genes, 132 of which are functioning genes, making it about six times more complex than the Syphilis spirochete. Bb evades the immune system with mutations, physical seclusion, and secreted factors. Scientists have just discovered the first toxic secretion by Bb, Porin (OMS28), which it probably uses to punch holes in cell membranes. http://iai.asm.org/cgi/content/abstract/72/11/6279 "


Smee: I've just had an apostrophe.
Captain Hook: I think you mean an epiphany.
Smee: No... lightning has just struck my brain.
Captain Hook: Well, that must hurt.
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