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HLA B-27 factor and Lyme Arthritic?



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01/25/2008 05:24
tina.r
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HLA B-27 factor and arthritic Lyme

I went to my Rheumatologist yesterday and all my labs were normal except the HLA B-27 factor. As far as I understand a lot of people that suffers with Chronic pain and auto- immune disorders are HLA B-27 positive. About 10% of the population has this and it does mean that you have a disorder, just that you are more prone for it. In my own research I have learned that 10 % of people with Lyme Arthritic never get rid of it. I therefore wonder if most of these 10 % have the HLA B-27 factor. Anyone out there with Lyme Arthritic that also is HLA B-27 positive. Is there a relationship?

My rheumatologist thinks that I will have to deal with what I have for the rest of my life. He also thinks that Lyme has caused some kind of onset of an auto-immune respond. He mostly bases this on the kind of aches and pains I have and states that because of my neck knee, feet and shoulder pain it is mostly not caused by Lyme. Why do docs. so often make something up that they do not know anything about. As far as I know pain in neck and knee is the most common pain caused by Lyme! Again, we are so much more educated most of the time than the docs. This time I will keep this for myself, my rheumatologist is good at dealing with un-diagnosable chronic pain and has been helpful with tha.

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01/25/2008 05:39
jaime1978
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sounds like he's full of ...SH** I'll be nice and leave the last two letters out. YES, lyme affects the large joints pain wise first...it LOVES the knees, and many of the other large joints.

from what I've researched is that what can be causing some lymeies to have more pain that others (I mean, some of us, like me, lay on the ground begging God to make it end, the pain is insane)....goes back to the cortisone I've had. It reactivates dormant viruses you've never even known you'[ve had!!! and they can be more painful and dangerous then lyme, some viruses can mutate and even turn into cancer!!! most lymeies who've had any sort of cortisone are usually the ones in the most pain....and the studies theyve been doing, it's because of these viruses... good news/bad news... can't cure it, but can hope to make it go dormant again... by taking Valtrex or something like it, an antivirul, valtrex is one of the best. it stops it from reproducing, not killing it.

I've never heard of the HLA B 27 thing, but who knows, there may be something too it... i'm no doctor, but I certainly know that lyme causes pain , most of the time in joints

Please do not take anything I say as medical advice. I am not a doctor.

~lyme disease support group leader~
please pm me with any special concerns
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01/25/2008 05:49
tina.r
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I really thought that I will recover fully but the HLA B-27 factor makes me concerned. I really wonder if that could be an indicator that the Lyme Arthritic might be stubborn. I will get on a lower dose of Modix today (7.5 mg) and see what happens. It took me a while to convince him to use less drugs rather than more. I'll keep you posted about what happens.

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03/08/2008 13:30
FT217
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I am in the same boat as you and am having some serious doubts about whether or not to accept what my rheumatolgist is telling me re:Lyme and my hla b27 factor.

She also indicates that this is something that will never leave me, and can be triggered by not only Lyme disease, but other factors, like food poisoning. She indicated to me that a maintenance program is the only way to make any difference in the way that I feel. The flair ups are killers and have lasted as long as 18 months for me.

I'm all for less meds, but at this point, I am just looking for relief.

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