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You all might find this article interesting ... Rituxan fails as lupus treatment Wednesday April 30, 2008 The drug Rituxan (rituximab), used for treating rheumatoid arthritis and non-Hodgkin's lymphoma, has failed as a treatment for lupus, according to results from a clinical trial. The trial was conducted by two biotechnology companies, Genentech and Biogen. The drug had also been in a trial as a multiple sclerosis treatment and failed in that as well, although hopes had been higher for a lupus treatment. The trial involved 257 patients, who received either Rituxan or a placebo. Rituxan did not outperform the placebo on seven effectiveness measures used in the trial. It has been 30 years since a new lupus drug has been introduced. Two other companies, however, have lupus drug trials underway. Human Genome Sciences is testing a drug that's akin to Rituxan and Bristol-Myers Squibb is testing Orencia (abatacept), a rheumatoid arthritis drug. |
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