hipmama42
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Substance P is an excitatory neurotransmitter which is found in increased quantities in the spinal fluid of fibro patients; it is involved in the transmission of pain signals to the brain. Hope this explains it better than I could;I lifted it from a website that talks about biochemical changes in fibromyalgia: "....Although the etiology of FM is not completely understood, the syndrome is thought to arise from influencing factors such as stress, medical illness, and a variety of pain conditions in some, but not all patients, in conjunction with a variety of neurotransmitter and neuroendocrine disturbances. These include reduced levels of biogenic amines, increased concentrations of excitatory neurotransmitters, including substance P, and dysregulation of the hypothalamic-pituitary-adrenal axis. A unifying hypothesis is that FM results from sensitization of the central nervous system. " if you are interested in the whole article, here is the site: http://www.fmaware.org/site/News2?page=NewsArticle&id=5690 " Post edited by: hipmama42, at: 02/01/2008 23:04 Post edited by: hipmama42, at: 02/01/2008 23:04 |
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