barbo, Here are a few Liver facts. 1) The liver creates Glucose Tolerance Factor (GFT) from chromium, niacin and possibly glutathione. GFT is needed for the hormone insulin to properly regulate blood-sugar levels. Due to its critical role in facilitating amino acid entry into muscle cells, GFT empowered insulin is also a necessary co-factor for Growth Hormone to be effective in promoting muscle growth in response to athletic training programs. 2) The liver serves as the main glucose buffer, preventing high or low extremes of blood sugar. It is the key regulator of blood sugar between meals, due to its manufacture, storage and release of glycogen. Glycogen is the starch form of glucose in which the body can store a half days sugar supply. When the blood sugar is low, a healthy liver converts stored glycogen into glucose, releasing it into the bloodstream to raise blood sugar levels. When blood sugar is to high, the healthy liver will remove much of it, converting the excess into stored glycogen or fat. 3) The liver can make glucose from dietary or body-derived amino acids. This process called gluconeogenesis or "the making of new glucose", ensures adequate brain and muscle carbohydrate fuel supplies even when the diet provides little or no carbohydrates. The liver produces as much as 20-25% of the blood sugar and endurance athlete's muscles might burn during intense training or competition by converting the amino alanine (released from muscle tissue) into glucose. So when the liver is damaged we have a rise in diabetes. Also diabetes can cause liver disease by causing Fatty Liver , NASH or Cirrhosis.Also the anti rejection drugs can cause diabetes. The two are closely related. Gail Gail
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